Latest issue
Sent: April 30, 2026
Global Action Community Newsletter
There have never been more solutions to help you quit smoking than there are today.
Quitting smoking has always been hard—and it remains the leading preventable cause of death worldwide today.
In the 1960s when scientists recognized the long-term health threats of smoking, there weren’t many options to support adults who wanted to quit. But today, you have a wide range of choices to help you on your quitting journey—which means there’s never been a better time to try to improve your health.
Nicotine is the addictive component of cigarettes. Nicotine replacement therapies have helped millions of people quit smoking by providing small amounts of nicotine to help reduce cravings as you move away from smoking.
In total, there are five kinds of nicotine replacement therapy that have been approved across the globe. These include the following forms of nicotine:
Gum
Patches
Lozenges
Inhalers
Nasal sprays
There are also several medications that help people quit smoking by acting on nicotine receptors in the brain. They can reduce cravings and withdrawal symptoms. The availability of these medications may vary depending on your location, but they include the following:
Varenicline
Bupropion
Cytisinicline
Beyond pharmaceuticals, digital tools have extended the way adults who smoke can access support. Several smartphone apps have emerged in the past decade.
Some of these products display the amount of money you’ve saved forgoing cigarettes. Others work like cessation programs, providing advice and encouragement periodically. Advanced apps can even track and respond to location, offering tailored support when the user is near a potential trigger that might lead them to smoke.
And even more recently, a class of reduced-risk nicotine products has emerged. These products contain nicotine, and are not risk-free, but are much less harmful than cigarettes.
Reduced-risk nicotine products aren’t official smoking cessation tools, but government authorities including the US Federal Drug Administration (FDA) recognize that switching entirely to these products significantly reduce a person’s long-term health risks. Some authorized products in this category include:
Heated tobacco products, which electronically heat up tobacco without burning it to create an inhalable aerosol that contains nicotine.
E-cigarettes, which heat up liquid to produce an inhalable vapor containing nicotine.
Nicotine pouches, which sit between the lips and gums, allowing nicotine to be absorbed without any heating mechanism or exposure to tobacco.
The goal of quitting smoking is to improve your long-term health. That means that the best way to quit is the one that works for you.
Wherever you are on your path to quitting, keep going. Each attempt at quitting is moving you closer to a healthier life.
All my best,
Matthew Walker, DrPH
Program Officer, Global Action to End Smoking
By the numbers
References: World Cancer Research Fund and Johns Hopkins University and the.
Global Action is not affiliated with this work.
Global action IN THE NEWS
In April, the U.S. Food and Drug Administration reauthorized certain heated tobacco products.
With this reauthorization, the FDA allows packaging for these products to display language stating “studies have shown that switching completely from conventional cigarettes to [these products] significantly reduces your body’s exposure to harmful or potentially harmful chemicals.”
These reauthorizations continue to provide adults who smoke with potential solutions for their journey to quit. This decision complements Global Action’s charitable mission to end combustible tobacco use.
Thank you for your support
Global Action is one of the only public health groups to embrace tobacco harm reduction as a means of meeting adults who smoke where they are, showing them empathy in their individual cessation journeys, and helping them—if they cannot or will not quit—to reduce their risks of death or disease from combustible cigarettes.
Your support increases the impact our grantees’ work can have on this cause. Together, we can build a future where no one suffers from tobacco-related disease.
Thank you for your support in the fight against smoking.
Get to Know Global Action
Global Action has awarded more than 175 grants to institutions that support the work of over 100 scientists, covering 46 countries on four continents.
Our organization is an independent, U.S. nonprofit 501(c)(3) grantmaking organization whose mission is to end combustible tobacco use, which remains the leading preventable cause of death globally. Through September 2023, Global Action received charitable gifts from PMI Global Services Inc. Global Action does not seek or accept funding from companies that produce tobacco or non-medicinal nicotine products.
To learn more about our work, visit our website.
Disclaimer: This newsletter does not provide medical advice. The information, including but not limited to, text, graphics, images and other material contained in this newsletter are for informational and educational purposes only and does not constitute providing medical advice or professional services. No material in this newsletter is intended to be a substitute for diagnosing or treating a health problem or disease. Those seeking personal medical advice should consult with a licensed physician or other qualified health care provider. Always seek the advice of your licensed physician or other qualified health care provider regarding a medical condition or with any questions you may have regarding treatment and before undertaking a new health care regimen. Never disregard professional medical advice or delay in seeking it because of something you read in this newsletter. No physician-patient relationship is created by this newsletter. Global Action doesn’t make representations, express or implied, with respect to the information provided here.
Sign up to receive
our monthly newsletter
Newsletter Archive
Issue #18– March 31, 2026:
Issue #17– February 27, 2026:
Issue #16– January 30, 2026:
Issue #15 – December 2, 2025:
Issue #14 – October 31, 2025:
Issue #13 – September 30, 2025:
Issue #10 – June 30, 2025:
Issue #9 – May 30, 2025:
Issue #8 – April 28, 2025:
Issue #7 – March 28, 2025:
Tobacco Harm Reduction Helps People Quit
Issue #6 – February 28, 2025:
Smart Nicotine Policy is a Social Justice Issue
Issue #5 – January 31, 2025:
You’re making progress.
Issue #4 – December 20, 2024:
Advancing science to help people who smoke quit.
Issue #3 – November 26, 2024:
Public Health has to Embrace Complexity to Move Forward
Issue #2 – October 24, 2024:
Read Science like a Scientist
Issue #1 – September 23, 2024:
Welcome to our Community Newsletter