Cambridge Design Partnership (CDP), an innovation partner based in the UK and the USA, explored the impediments to mass adoption of reduced-risk products (RRPs) in LMICs, specifically Russia, China, India, and Indonesia. The Impediments to tobacco harm reduction in LMICs report outlines CDP’s research findings and discusses the range of impediments to RRP adoption, particularly the public’s general lack of acknowledgment that they are at risk from combusted tobacco use, which diminishes the drive to seek RRPs.